Category Archives: disease

Books where disease or sickness is a theme.

August 16, 2012 · 5:00 am

Review 188: The Immortal Life of Henrietta Lacks

The Immortal Life of Henrietta Lacks by Rebecca Skloot

Henrietta Lacks has probably saved your life. If not yours, then almost certainly that of someone you know.

And you don’t even know who she is.

Or, rather, who she was. The original Henrietta Lacks was an African-American woman who lived near Baltimore, grew up in poverty, worked hard, and died in 1951, overcome by a cancer that started in her cervix and spread out to take over her whole body. She left behind five children, a husband, and a legacy that would forever change our understanding of biology and medicine.

This picture is required to be inserted into any discussion of Henrietta Lacks, for good reason.

When she first went to Johns Hopkins Medical Center and was diagnosed with cancer, her doctor took a small sample of cells from the tumor and sent it to his colleague, George Gey. Gey had long been in the pursuit of what seemed like an impossible dream: to culture human cells and keep them alive in the lab. By doing so, he hoped to create new ways to test medicine and study human biology without all those pesky patients getting in the way. Unfortunately, his work had thus far been a failure. Human cells, no matter how hard he tried, simply would not survive outside the body for very long. Gey tried all kinds of media and methods, inventing some machines that have become invaluable to cell culture research, but he simply watched culture after culture die in the lab.

All of that changed when he got HeLa.

The cells from Henrietta Lacks, which were known as “HeLa,” not only didn’t die – they thrived. They were so robust that Gey and his staff soon had more HeLa cells than they could keep, much less use, so they started sending them off to any researcher who asked. With HeLa, researchers around the world began to make discoveries that would save lives and change the world.

But with this ever-growing cell line – which was baked, boiled, frozen, irradiated, cloned, cut up, and sent into space – it was very easy to forget that there was once a woman named Henrietta Lacks, with a family and a legacy of her own.

Plenty has been written about HeLa in the last fifty years, and any researcher who works with cells is probably well aware of its existence and importance. But very few people know about Henrietta, and it was this oversight that Rebecca Skloot is trying to correct in this book.

Henrietta finally gets a gravestone

She began her quest with a simple question: “Who was Henrietta Lacks?” The fact that she got the right name was surprising enough, actually. HeLa had previously been identified as Henrietta Lakes, Helen Lane, and Helen Larson in various publications. Skloot believed that there was more to the story than just a bunch of immortal cells, and was determined to find Henrietta’s surviving relatives and learn more about this woman who had somehow become so important to the world.

Skloot wouldn’t be the first, however. A writer for Rolling Stone, a con man, and the BBC had all attempted to look into the life of Henrietta before, and found that the surviving Lackses were not only unaware of what their mother had become, but largely unaware of why it was important.

The children and grandchildren of Henrietta Lacks had grown up in the Baltimore area, mired in the poverty of being black in the end of the twentieth century. Drug abuse, alcoholism, and a lack of education meant that their lives were full of hardship and struggle, and not likely to get any better. When they found out that Henrietta’s cells were not only unique to science but being sold all around the world, this was news that they weren’t all prepared to cope with. Some saw it as a religious visitation, others as a massive conspiracy, and still others as just a way to make money off some poor black folk from the city.

Deborah Lacks

The center of Skloot’s narrative is Deborah, Henrietta’s youngest daughter and the one Lacks who seemed most determined to find out what had happened. Deborah wanted so hard to find out what had happened to her mother that it almost killed her. The stress of not knowing – or, even worse, knowing but not understanding – took a heavy toll on her physical and mental health, and she was reluctant to talk to anyone at all about her mother. But it was Deborah that Rebecca had to convince if she was going to write this book, and in order to do that, she had to promise that the book would be about the woman Henrietta was, not just the cells she was famous for.

That’s probably what makes this book as readable and engaging as it is. While the science is handled well and smoothly, it’s not nearly as fascinating or emotionally gripping as the stories that she tells about the Lacks family. She shows us a family that is held together by the strength of their faith in their God and each other, and who are desperately trying to understand their place in the world and how Henrietta came to be what she was.

HeLa cells, as seen stained under a microscope

When the original cells were taken from Henrietta, it was done without her consent. She also had no say in what happened to those cells and how they were used, nor did any of her family find out the truth until years later. In an era long before the phrase “informed consent” was even coined, the medical establishment made massive scientific and financial gains, and in the meantime the Lacks were mired in poverty. As several of her children note, Henrietta has changed medicine forever, but her children can’t go see a doctor.

The struggle to understand must have been enormous. One of the moments that was most surprising and illuminating to me was when Henrietta’s son Zakariyya asked Rebecca, “What’s a cell?”

Just like Rebecca, I had to take a moment to absorb that question, and it put into sharp perspective the vast assumptions that I had made, coming from a well-educated white background. I thought that everyone at least knew what a cell was, but that assumption couldn’t have been further from the truth. Deborah and her family are people of minimal formal education who are trying to understand a topic that people study for their entire lives. Their dedication to this quest is so strong, and the struggle is so great that their attempt is nothing less than heroic, to my way of seeing things.

The Lacks Family

The story is still unfinished. HeLa is still out there, making news and causing trouble. The Lacks family is still living in poverty, although the new generation has been able to go to school and are aiming at a brighter future for themselves. And while patients’ rights to control what is done with their bodies and their tissues is improving, the law is still on the side of the doctors and hospitals. Medical ethics is a lot better than it was, but the fight is fierce, especially when there’s money involved.

This book is not just the story of cells or of science. It’s the story of a woman and her family, and how sometimes people get lost in the inexorable movement of scientific progress. Some parts are infuriating, some are heartbreaking, but the book is an illumination into what is sometimes sacrificed in pursuit of a better world.

—–
“When I saw those toenails, I nearly fainted. I thought, Oh jeez, she’s a real person. I started imagining her sitting in her bathroom painting those toenails, and it hit me for the first time that those cells we’d been working with all this time and sending all over the world, they came from a live woman. I’d never thought of it that way.”
– Mary Kubicek, assistant to George Gey

Rebecca Skloot on Wikipedia
Henrietta Lacks on Wikipedia
The Immortal Life of Henrietta Lacks on Wikipedia
The Immortal Life of Henrietta Lacks on Amazon.com
The Henrietta Lacks Foundation website
The Lacks Family website
Rebecca Skloot homepage

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November 17, 2011 · 5:00 am

Review 149: Speaker for the Dead

Speaker for the Dead
by Orson Scott Card

In his introduction to the book, Card says that the main reason he wrote his most famous book – Ender’s Game – was so that he would one day be able to write this. I think this is something that probably happens a lot to authors. They get a Big Idea in their head, something with great depth and complexity and meaning, and quickly discover that they don’t actually know what they’re writing about yet. There’s too much to say, there’s too much that even the author doesn’t know yet, and to go forward from that state of ignorance will result in what is, ultimately, an inferior narrative.

Andrew Wiggin, the Speaker for the Dead, comes to the human colony Lusitania in order to speak the death of a local man, Marcão. While given the same reverence and privileges as priests, Speakers are not the same. Their job is to learn about the dead, to understand who they were and who they wanted to be, and then tell the truth as plainly and as clearly as possible. They do not give eulogies, where they try to paint the dead in as good a light as possible. They reveal who this person was, and in the process try to help those left behind understand them. It’s a calling that requires an insightful mind, great empathy for others, and the ability to tell the truth despite how hard that truth may be to hear.

As a Speaker for the Dead, Andrew Wiggin is very good at his job. It was he who was the first Speaker, who wrote a text that is as revered as the Bible – The Hive Queen and the Hegemon – in order to understand how humankind could kill the only other intelligent species it had ever encountered. The book reveals who the Buggers were and why they attacked humanity. It tells how their understanding of what it means to be intelligent led to a century of warfare and, ultimately, their own destruction. The book also reveals humanity, the dreams and fears that it faced when it met the Buggers. And it tries to understand why humans were so afraid that they took one of their own – a little boy named Ender – and turned him into the greatest monster in human history. The Xenocide. The one who destroyed an entire alien race.

This book changed the way humankind saw the universe, and themselves. With the Buggers gone, but their technology still available, humans expanded out to a hundred worlds. Though their starships could only go just under the speed of light, the ansible provided instant communication between the stars. It formed a communications network that held the Starways Congress together and allowed humanity to become a multi-system species.

Ender – Andrew – is ultimately responsible for all of this, and is therefore the linchpin of this entire universe. In order to write this book, to understand the culture and the history and the politics that would be necessary to write Speaker for the Dead, Card first had to understand who Ender was. So, with the blessing of his publishers, he was able to turn Ender’s Game into a full-length novel. Once that was done, he was able to turn back to this book and craft it into what it has become.

Question: Will the aliens wear hats that are sillier than ours? No? Good.

The colony of Lusitania is a small place, a group of Catholic settlers who live in a small and insular town. They have all the troubles that any new world would have, except for two that make it truly unique. The first is the descolada, a virus that nearly destroyed the colony and, thousands of years before, life on the planet. This illness literally unzips and recombines your DNA, ravaging your body utterly. If not for the dying work of the colony’s two great xenobiologists, everyone would have died. As it turned out, Gusto and Cida were the last to die, leaving their sad, strange daughter Novinha behind.

Even that wouldn’t be enough to make Lusitania a truly remarkable place. No, for that, we must introduce the Piggies – the third intelligent life form known to exist in the universe. They’re small, look like little pig-men, and are indisputably intelligent. They learn quickly, even despite the law forbidding xenologists from influencing their development, and present humanity with an important chance: the last time we encountered an alien intelligence, we obliterated it. Let’s not do that again.

This becomes harder, however, when the Piggies kill two of the xenologists in what appear to be a horrifyingly painful method. Now it looks like humanity may have to revert to type again, and that there truly is no way that humans can share the same space with other intelligences.

Into all this steps Ender. His years of lightspeed travel have kept him young while three thousand years have passed, and he has wandered from world to world to speak for the dead. Now he is on Lusitania to speak for Marcão, an investigation that will lead him to uncover secrets kept for decades, and to once again change the way humans understand their universe.

There’s really so much to say about this book that it’s hard to decide what to leave out and what to keep in. For one thing, Card is trying to write a very different kind of science fiction story. In his introduction, he says that a lot of fiction is adolescent in nature, science fiction especially. It’s about adventure, about people seeing a way out of their conventional lives and going off alone. It’s about being freed from responsibility and living a fast and crazy life. When that loneliness of adventure finally becomes too much, the hero settles down, but that’s usually the last chapter of the book, if ever.

Isolation. Not just for murderous adolescent geniuses.

Card wanted to go the opposite way, to take a lonely adventurer and show him trying desperately to become responsible, to become a member of a community. In class, where I’m teaching Ender’s Game, we’ve identified isolation as being one of the overriding themes of the novel. Ender is constantly taken away from those he loves or held apart from others. In the end, he becomes a solo wanderer. Even more than that, he is made into a monster, a name on par with Lucifer itself. He is virtually thrown out of humanity, and it is only because no one knows who he really is that he can travel unmolested.

So we’re seeing Ender in that stage where the loneliness and the wandering have become an unbearable burden to him, and all he wants is a place to belong. But as a Speaker, as a man speaking a death that could completely upend the lives of everyone in the colony, he has his work cut out for him.

There is also the element of redemption. In his years of travel, Ender has carried a very special package with him – the cocoon of the last Bugger hive queen. In exchange for her story, he promised that he would find a home for her, a place for her to rebuild her vast family. And on Lusitania, there is that chance. But first he has to save the Piggies, to prevent them from suffering the fate of the Buggers at the hand of a fearful and suspicious Humanity. If Ender can do this, perhaps he can make up for the horror that he unknowingly perpetrated.

There’s a lot going on in this book, to say the least. It’s a great book, better in many ways than Ender’s Game. It is more complex and adult and difficult, with moments of true emotion, a well-built socio-political system befitting a species that spans hundreds of worlds, and addressing the needs for changes in culture, politics and even language that would arise from the need to define relationships between worlds and between species.

Ender would have been a natural for the Indigo Tribe. You listening, Geoff Johns?

Fundamentally, though, this book is about what the Speaker for the Dead does best – understanding. It’s about how we deal with The Other, even when that Other is completely alien to us. Humans and Buggers, Humans and Piggies – hell, Humans and Humans, we have a hard time understanding people who are not like us. We find it very difficult to look at the world from their point of view and to see the world through their eyes. Understanding what they love and fear, what they value and honor, or what they abhor – and more importantly, understanding what they see in you and how they understand you – is the best and surest road to making peace with those who are different from yourself. And that’s a lesson that is valuable for all of us.

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“No human being, when you understand his desires, is worthless. No one’s life is nothing. Even the most evil of men and women, if you understand their hearts, had some generous act that redeems them, at least a little, from their sins.”
– Ender Wiggin, Speaker for the Dead

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Filed under children, colonization, death, disease, empathy, family, friendship, morality, murder, Orson Scott Card, science fiction, sins, society, space travel, teenagers, women

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September 10, 2009 · 12:00 am

Review 35: The Andromeda Strain


The Andromeda Strain by Michael Crichton

Michael Crichton passed away recently, so I thought he would be a good choice to read. I know there are people who have problems with Crichton – his later books revealed some distinct political leanings and display very clear biases, the most obvious of these being State of Fear, in which he attacks the environmentalist movement’s support of global warming. His attacks are blatant, and even though the novel is said to be a good read, it’s burdened by the obvious slant of the author.

It’s tough to know what to do with authors who inject their own personal morality into their works. Some of them, like Heinlein, do it in such a way that it’s not a distraction – it’s Heinlein. Others, such as Orson Scott Card, are so vocal in their political opinions that they risk losing a large portion of their readership. In this situation, you have to make a decision: read the book for the story or read the book for the author’s politics? Or don’t?

I take the same route here that I do with actors, musicians and other artists who make their political and social views known. I disregard those views and just judge their work on its own merits. It’s not that hard to do, really….

Anyway, I remember seeing this movie for the first time, and it scared the hell out of me. Not in the same way that my childhood slasher films scared me, of course. In those, there was always someone – Jason, Freddie, Michael – who was lurking behind curtains, waiting to turn you into steak tartar if you were foolish enough to have sex in the camp counsellor’s cabin. But at least they were human (sort of), and they had motivations, however insane these motivations were.

In this book, we are not facing a psychopath with a chainsaw. It’s something more terrible and more impossible to deal with.

The premise – The US space program, in an attempt to figure out exactly what is lurking in the upper atmosphere, has been sending up special satellites – the Scoop satellites – to sample the air up there and then return so that scientists can do what they do best. The theory was that if we were to encounter extraterrestrial life, the odds are that it would be some sort of simple organism rather than a four-foot grey humanoid.

People like Carl Sagan seemed to support this theory, and Crichton makes a very good case for it through his characters. Radio waves attenuate, even light pulses can’t last forever – but build an organism that can survive indefinitely in space? That is an excellent way of telling the rest of the universe that you’re out there. A microbe needs a lot less to keep it going than your average movie E.T., so it would be reasonable to assume that it would make an excellent message in a bottle in a vast and harsh cosmos.

Back to the book – most of these satellites went up and came down without incident, but one – Scoop VII – had some unexpected problems and crashed in the American southwest, just outside a small town called Piedmont. The good citizens of Piedmont, wanting to know what it was, brought it home to have a look.

Within eighteen hours, nearly everyone in Piedmont was dead. The lesson? Never go near something that comes screaming out of the sky. Yes, it might give you super-powers, but odds are that it’ll kill you.

The government, always looking for the worst case scenario, had planned for this, and put Project Wildfire in action. Wildfire called for a team of scientists with varied backgrounds to be brought to an isolated lab in Nevada. Scoop would be brought there, and they would attempt to unravel the mystery of what killed the people of Piedmont.

The story sounds pretty simple, and Crichton makes a point of saying that, ideally, there should be no story to tell. Wildfire facilities are insanely well-guarded, and the design of the complex itself is nearly foolproof against something escaping – to the point that, if the facility becomes insecure, it will be vaporized in a nuclear explosion.

As usual, Crichton is meticulous in his science. The book has a bibliography in the back with 58 references to justify his use of x-ray crystallography, culture growth, electron microscopes, and other theories. The point is, he is saying that the incident in The Andromeda Strain could happen. Maybe. And it is possible that, despite our best planning and efforts, we might not be able to stop it.

This brings up the question: is this really science fiction? Well, yes, because A) it’s fiction and B) the story is dependent on the science. But it’s not science fiction in the way that we’re familiar, since very little of it is actually fictional. Most of the technology is extant, and the tech that is a little more outlandish is certainly within our ability to create. The only thing that is really speculative is the Andromeda organism itself. And even given that, the story is not so much about the organism as it is about the race to figure out what the organism is – it’s about the scientists, not the science.

Where the actual story comes in is with the introduction of Mistakes. A simple malfunction in a piece of communications equipment. A medical problem that is hidden until it is too late. Miscommunication and assumption abound, which is what makes this book interesting. Otherwise, it would just be a matter of the scientists trying to figure out what this wee beastie that hitched a ride on Scoop can do, and why. Perhaps it’s not so much science fiction as it is scientific fiction. If that makes any sense….

Indeed, the silly humans are saved from worldwide extermination by virtue of the microorganism’s own nature, oddly enough. This isn’t The Stand – Crichton didn’t set out to write an End of the World story. He wanted to talk about science and what might happen if an unknown pathogen should appear from the darkest regions of space.

As I said before, this is what makes it so terrifying. The villain of this story is a bacteria. We don’t know where it comes from, how it works, or why. It has no ambition, no plan. It is not hostile, malicious, or vindictive. It can’t be bargained with or tricked.

Perhaps that is why disease stories are so interesting. On the one hand, they point out how vulnerable we really are to something we have never encountered. On the other hand, they show how sometimes, just sometimes, we can avert disaster with the ingenuity that keeps popping up in humanity.

So – it’s well-written and well-researched, not to mention a sci-fi classic. The movie’s pretty good as well, and sticks relatively close to the book. Either are recommended.

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“He [Stone] often argued that human intelligence was more trouble than it was worth. It was more destructive than creative, more confusing than revealing, more discouraging than satisfying, more spiteful than charitable.”
– Michael Crichton, The Andromeda Strain
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Michael Crichton on Wikipedia
The Andromeda Strain on Wikipedia
The Andromeda Strain on Amazon.com
NASA’s Exobiology Branch

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May 28, 2009 · 12:00 am

Review 20: The Doomsday Book

The Doomsday Book by Connie Willis

I honestly can’t count the number of times I’ve read this book. I think this is the fifth time. Or maybe the sixth, I don’t know. It doesn’t really matter, because it’s just as enjoyable, touching and heartbreaking as it was the first time I read it, and that’s a hell of an accomplishment.

It is the middle of the 21st century and time travel has finally been worked out. A reliable there-and-back-again way to go into the past and come back to the present. Unfortunately, there are limitations. The computer that makes time travel happen, through means I’m not sure even Ms. Willis understands, will not allow for a paradox. This means if you try to go to the past with anachronistic technology, or carrying a disease that could wreak havoc on the population, the interface simply won’t open. If you try to place a traveler somewhere where their appearance could cause a paradox, the machine will put them in another place or time – a factor called “slippage” which can put you anywhere from five minutes and a few feet off your mark to years and miles. The machine won’t allow you to get anywhere near events of importance.

Secondly, the machine won’t allow you to take anything through the net. So if you travel to, say, Napoleon’s palace and try to rob him blind, the interface won’t open until you’ve got rid of all your booty.

Those two factors alone made the time machine economically useless. If you can’t profit off it – or change it – what good must it be?

A lot of good, as it turns out, if you’re an historian. While the machine may not allow you to get anywhere near Hitler, it will allow you to see what life was like in the ghetto in the 30s. The whole of history suddenly became open to real discovery, and places like Oxford were at the forefront of the research.

One student, a young lady named Kivrin, has a dream to see the Middle Ages. Despite all the warnings that it was full of filth, disease, superstition, danger and death, she still wants to see it more than anything in the world. The sheer force of her will finds her in the machine, ready to go to the year 1320 to see firsthand what life was like for the average English citizen. She has prepared herself as best she could, but nothing could possibly prepare her for the time and place she ends up in….

And in the present, a new plague has spread around Oxford. It’s a new type of flu that seems to have come from nowhere, and it’s started to kill. Kivrin’s teachers and friends have to race the disease, time and sheer bloody-minded bureaucracy to try and find her and bring her back safely.

What is remarkable about the book is the detail. Willis has obviously done a lot of research into not only Medieval Oxford but modern Oxford as well. Since one of the themes of the book is that we don’t know nearly as much about the past as we think we do, Willis has gone to great lengths to make sure that we – through the eyes of Kivrin – never know what to expect because our expectations are all totally wrong. And as is so often true about history, the more we know about it, the more interesting it becomes.

The Oxford of the future, by contrast, isn’t all that futuristic. It looks a lot like the modern world, probably because it’s only a couple of decades removed from us. Sure, there have been advances in technology, but the lives of the people aren’t much different from ours.

Interesting note: the book was published in 1992, well before the age of cell phones, instant messaging and the internet. Because of this, one of the greatest hindrances to getting anything done in this far-future Oxford is that no one can get anyone on the phone. It’s a videophone, yes, but most of the characters spend time waiting for phone calls to come through or trying to place calls to people who aren’t near a terminal. It’s a bit strange, from my modern perspective, to see a world that has pretty much conquered disease and mastered time yet never figured out a means of personal communication better than a land-line.

That’s just a small thing, though, and as long as you accept that particular bit of alternate-future, you’ll be okay. It’s a fantastic book, one which I recommend without reservation. The characters are deep and interesting, and the writing really puts you in their world. Seriously. Go get it.

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“Mr. Dunworthy, ad adjuvandum me festina.”
(“Mr. Dunworthy, make haste to help me.”)
– Kivrin, The Doomsday Book
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The Doomsday Book on Wikipedia
Connie Willis on Wikipedia
The Doomsday Book on Amazon.com
The 11th-Century Domesday Book at Wikipedia
The Domesday Book online

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Filed under Christmas, Connie Willis, death, disease, England, science fiction, survival, time travel

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May 7, 2009 · 12:00 am

Review 17: The Stand

The Stand by Stephen King

It’s hard to know where to begin when writing about this book, probably because I work under the assumption that everyone has read it. I mean,. I’ve probably owned at least four different copies over the years, and it occupies a permanent place on my bookshelf. I can’t imagine anyone not having read it. But I guess that’s what everyone thinks about their favorite books, so I’ll fill in those of you who haven’t.

It’s the end of the world. Not in the horrible confluence of blindness and carnivorous plants, or in the fiery desolation of nuclear war. The world dies in a more unpleasant way than that, and it all begins in Project Blue – a US military lab in the southwest. There they’ve built the greatest plague mankind has ever known, a shapeshifting flu virus that is 99.4% communicable and 100% lethal. Its intended use was probably against the Soviets or some other enemy state, but… Things fall apart, the center cannot hold, as Yeats said. And on June 13th, 1990, the superflu got out.

It was carried by Charles Campion and his family, spread throughout the southwest until Campion died in a gas station in Arnette, Texas. From there it hopped into the men gathered at the station, who passed it on to nearly everyone they met.

By June 27th, most of America was dead. And thanks to the final command of the man in charge of Project Blue, the virus was spread around the world as well. By Independence Day, the population of the world – that which by some strange genetic luck was immune – was reduced to less than the pre-plague population of California.

Of course, not everyone who was immune escaped unscathed. There were accidents, mishaps and murders that probably brought the number down, but not by much. Scattered survivors struggled to understand why they lived when so many had died, and started to seek out others like them.

And then came the dreams. An ancient woman, living in a cornfield. She radiates goodness and compassion (and still makes her own biscuits). Mother Abagail is the beacon of hope for those who see her in their dreams. And then there’s the other, the Dark Man, the Walkin’ Dude, whose shadow brings madness and whose gaze brings death. He is Randall Flagg, a man whose time has come ’round at last. Just as Mother Abagail attracts the good and strong, so does Flagg attract the weak and frightened. Around these two do the remains of America come together. And neither one can let the other exist without a fight….

What keeps bringing me back to this book? Well, a lot of things. For one, the writing. King has said that he’s a little disturbed about The Stand being the fans’ favorite – it means he did his best work thirty years ago. Not entirely true, I think, although I am hard pressed to say which of his other books exceeds it. King’s sense of scale as a writer is outstanding. We get into our characters dreams, in their innermost secret thoughts, and then a few pages later are presented with an overview of what’s happening around the nation. It’s like being able to go, in Google Maps, from someone’s bedroom all the way out into space. He dances between characters smoothly, so just when you get to the point where you’re thinking, ‘Yeah, but what’s Flagg doing?” he brings you there.

And speaking of the characters, they’re people who will stay with you long after you finish the book. The quiet confidence of Stu Redman, the single-minded madness of the Trashcan Man, Larry Underwood’s late maturity, Lloyd Henreid’s devotion, Fran Goldsmith’s determination…. Each character rings true. Even the ones who really shouldn’t have ended up the way they did – and I’m thinking of Harold and Nadine here – you can’t help but find bits of them to love. Had they been strong enough, Harold and Nadine never would have gone as bad as they did, and I think even King kind of had a hard time making them do what he wanted.

Underlying all this, of course, is a kind of Old Testament religiosity. The God of Mother Abigail is not the kind and friendly God of the New Testament, He is the angry one of the Old. He is the God who will gladly wipe out nearly all of mankind to prove a point, and will make a 108 year-old woman walk into the desert by herself because she’s getting a little too uppity. In this world, at least, God is most definitely real, even though His purpose is hard to understand.

I could go on. Thesis papers could probably be written about this book, and I reckon they already have been. But that’s not why I do these reviews. I do them because I want y’all to know what’s worth reading.

This book is worth reading.

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“Show me a man or a woman alone and I’ll show you a saint. Give me two and they’ll fall in love. Give me three and they’ll invent the charming thing we call ‘society’. Give me four and they’ll build a pyramid. Give me five and they’ll make one an outcast. Give me six and they’ll reinvent prejudice. Give me seven and in seven years they’ll reinvent warfare. Man may have been made in the image of God, but human society was made in the image of His opposite number, and is always trying to get back home.”
– Glen Bateman, The Stand
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The Stand at Wikipedia
Stephen King at Wikipedia
The Stand at Amazon.com

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